Responsive electrical stimulation for movement disorders
AssigneeNeuroPace, Inc.
InventorsThomas K. Tcheng, Robert E. Fischell, Benjamin D. Pless
Life of this patent
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Abstract
An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of applying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected.
Claims12
A method for treating a movement disorder in a human patient with an implantable neurostimulator comprising:
- receiving and continuously monitoring a signal from a sensor configured to sense electrical activity of the brain;
- processing the signal to digitize it;
- analyzing the signal to determine whether a tremor characteristic of an episode of the movement disorder is occurring, wherein analyzing the signal comprises:
- measuring an amplitude of the signal;
- calculating an average amplitude of the signal over a predetermined period of time;
- comparing the average amplitude to a dynamic threshold that is a fixed offset of a long-term moving average amplitude wherein the long-term moving average amplitude is calculated from data in which no tremors occur;
- and
- detecting a tremor event if the calculated average amplitude exceeds the dynamic threshold;
- and
- delivering a treatment to the patient from the neurostimulator for so long as the tremor event is detected and ceasing delivery of the treatment when the tremor event is no longer detected thereby delivering a therapy from the implantable neurostimulator in response to the tremor.
A method for treating a movement disorder in a human patient with an implantable neurostimulator comprising:
- receiving and continuously monitoring a signal from a sensor configured to sense electrical activity of the brain;
- processing the signal to digitize it;
- analyzing the signal to determine whether a tremor characteristic of an episode of the movement disorder is occurring, wherein analyzing the signal comprises:
- measuring an amplitude of the signal;
- calculating an average amplitude of the signal over a predetermined period of time;
- comparing the average amplitude to a dynamic threshold that is a predetermined percentage greater than a long-term moving average amplitude wherein the long-term moving average amplitude is calculated from data in which no tremors occur;
- and
- detecting a tremor event if the calculated average amplitude exceeds the dynamic threshold;
- and
- delivering a treatment to the patient from the neurostimulator for so long as the tremor event is detected and ceasing delivery of the treatment when the tremor event is no longer detected thereby delivering a therapy from the implantable neurostimulator in response to the tremor.
Dependencies are inferred from the claim text.