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US 7,811,804 B2Granted
Nitrilases, nucleic acids encoding them and methods for making and using them
AssigneeVerenium Corporation
InventorsGrace DeSantis, Jay Short, Mark Burk, Kelvin Wong, Kelly Chatman, Bob Farwell
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Abstract
The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
Claims14
An isolated, synthetic or recombinant polypeptide having a nitrilase activity comprising a polypeptide having a sequence with at least 90% sequence identity to SEQ ID NO:210, or an enzymatically active fragment thereof.
Dependencies are inferred from the claim text.