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US 7,803,931 B2Granted
Aptamer therapeutics useful in the treatment of complement-related disorders
AssigneeArchemix Corp.
InventorsClaude Benedict, John Diener, David Epstein, Dilara Grate, Sara Chesworth Keene, Jeffrey Kurz, Markus Kurz, Thomas Greene McCauley, James Rottman, Kristin Thompson, Charles Wilson, Anna J. Zoltoski
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Abstract
The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders.
Claims5
A compound consisting of the nucleotide sequence according to SEQ ID NO:
- 4 and having a PEG polymer of 40 kDa conjugated via a linker to the nucleotide sequence's 5′ end.
A compound having the PEGylated aptamer according to SEQ ID NO:
- 65.
Dependencies are inferred from the claim text.