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US 7,803,917 B2Granted
Breast cancer resistance protein (BCRP) and antibodies thereto
AssigneeUniversity of Maryland
InventorNaoko Takebe
Life of this patent
Estimating the term…
Abstract
The present invention provides a breast cancer resistance polynucleotide and protein of Macaca mulata (rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.
Claims11
An isolated antibody, or an antigen-binding fragment thereof, which specifically binds to the rhesus monkey BCRP polypeptide of SEQ ID NO:
- 2 and does not cross-react with human BCRP polypeptide of SEQ ID NO:
- 6, SEQ ID NO:
- 7 or SEQ ID NO:
- 8.
1 more element
Dependencies are inferred from the claim text.