Choline esters useful for the treatment of cognitive dysfunctions and enhancement of memory, learning and cognition
AssigneeHass Patel
InventorHasmukh B. Patel
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Abstract
The present invention provides compounds of formula I described herein. The present invention also provides a method of treating a cognitive dysfunction in a mammal. The method includes administering to the mammal an effective amount of a compound of formula I described herein (e.g., stearyl choline chloride).
Claims13
A method of treating a cognitive dysfunction that is a nonvascular dementia or a nonvascular cognitive impairment in a mammal, the method comprising administering to the mammal an effective amount of a compound of formula (I):
- wherein,
- X is a pharmaceutically acceptable counterion;
- or a pharmaceutically acceptable salt thereof,
- wherein the nonvascular dementia or nonvascular cognitive impairment is Alzheimer's disease (AD), Huntington's disease or Parkinson's disease.
A method of improving cognition functions in a mammal suffering from Alzheimer's disease type dementia, the method comprising administering to the mammal an effective amount of a compound of formula (I):
- wherein,
- X is a pharmaceutically acceptable counterion;
- or a pharmaceutically acceptable salt thereof.
A method of treating, in a mammal, dementia associated with Alzheimer's disease, the method comprising administering to the mammal an effective amount of a compound of formula (I):
- wherein,
- X is a pharmaceutically acceptable counterion;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.