Utilization of dialkylfumarates
AssigneeBiogen Idec International GmbH
InventorsRajendra Kumar Joshi, Hans-Peter Strebel
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Abstract
The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.
Claims21
A method of treating at least one autoimmune disease selected from autoimmune polyarthritis and multiple sclerosis, but not treating psoriatic arthritis, comprising administering, to a patient in need of treatment for said at least one autoimmune disease but not for said psoriatic arthritis, an amount of a pharmaceutical preparation effective for treating said at least one autoimmune disease, the pharmaceutical preparation comprising
- at least one excipient or at least one carrier or at least one combination thereof;
- and
- dimethyl fumarate,
- wherein the only active ingredient for the treatment of the at least one autoimmune disease present in said pharmaceutical preparation is the dimethyl fumarate.
Dependencies are inferred from the claim text.