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US 7,803,785 B2Granted
Gemcitabine prodrugs, pharmaceutical compositions and uses thereof
AssigneeXenoPort, Inc.
InventorsMark A. Gallop, Ge Peng, Thomas F. Woiwode, Kenneth C. Cundy
Life of this patent
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Abstract
The present invention provides gemcitabine prodrugs, methods of making gemcitabine prodrugs, pharmaceutical compositions of gemcitabine prodrugs and methods of using gemcitabine prodrugs and pharmaceutical compositions of using gemcitabine prodrugs to treat or prevent diseases or disorders such as cancer or viral infections.
Claims18
A compound of Formula (I):
- or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable hydrate of any of the foregoing, wherein:
- R3 is —NHR12, wherein R12 is C6-9 acyl.
Dependencies are inferred from the claim text.