Peptides based on the sequence of human lactoferrin and their use
AssigneePharmaSurgics in Sweden AB
InventorsLars A. Hanson, Lars Baltzer, Inger Mattsby-Baltzer, Gunnar T. Dolphin
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Abstract
The invention relates to new peptides formed of at least seven subsequent amino acids of the amino acids in position 12-40, counted from the N-terminal end, in the sequence constituting human lactoferrin, and preferably modifications thereof. The invention also relates to medicinal products comprising such peptides, especially intended for treatment and prevention of infections, inflammations and tumours. Furthermore, the invention relates to food stuff, e.g. infant formula food, comprising the above mentioned peptides.
Claims20
A purified peptide comprising Phe-X1-Trp-X2-Arg-X3-Met-Arg-Lys-X4-Arg (SEQ ID NO:43) wherein X1, X2, X3, and X4 are, independently of each other, Gln, Lys, Asp, Asn, or Val, and wherein the peptide is selected from the group consisting of SEQ ID NOS:6, 7, 52-61 and 98.
Dependencies are inferred from the claim text.