Tropoelastin derivatives
AssigneeThe University of Sydney
InventorAnthony S. Weiss
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Abstract
The invention relates to derivatives of tropoelastin and variants of those derivatives. The invention further provides expression products and hybrid molecules of the derivatives and variants of the invention. The invention further provides methods for the production of the derivatives, variants, expression products and hybrid molecules. Further provided are formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention. Further provided are uses of the derivatives, variants, expression products and hybrid molecules of the invention.
Claims7
An isolated polynucleotide encoding a tropoelastin polypeptide wherein the polynucleotide has one or more of the following sequences:
- (a) the nucleotide sequence from position 9 to position 1676 of SEQ ID NO:1 contiguous with position 1776 to 2201 of SEQ ID NO:1;
- (b) the nucleotide sequence from position 1554 to 1676 of SEQ ID NO:
- 1 contiguous with 1776 to 2201 of SEQ ID NO:
- 1;
- and
- (c) the nucleotide sequence from position 1663 to 1676 contiguous with 1776 to 1791 of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.