Back to results
US 7,803,408 B2Granted
Method of treating endothelial injury
AssigneeEast Carolina University
InventorsGeorge Sigounas, Athanasius A. Anagnostou
Life of this patent
Estimating the term…
Abstract
The use of human erythropoietin (EPO) to prevent or treat endothelial injury due to chemotherapy, radiation therapy, mechanical trauma, or to a disease state which damages the endothelium (such as inflammation, heart disease or cancer) is described. The use of EPO in conjunction with the administration of chemotherapeutic agents is described.
Claims3
A method of treating a solid vascularized tumor in a subject in need of such treatment, comprising administering erythropoietin in conjunction with cisplatin;
- wherein said erythropoietin is administered in an endothelial growth suppressing amount, wherein said amount is a dosage in a range from about 750 Units per kilogram to about 2,000 Units per kilogram, and wherein the solid vascularized tumor is a cerebellar hemangioblastoma.
Dependencies are inferred from the claim text.