Reoviruses having modified sequences
AssigneeOncolytics Biotech Inc.
InventorMatthew C. Coffey
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Abstract
The invention provides for modified reovirus nucleic acid sequences and modified reovirus polypeptide sequences as well as reoviruses containing such modified nucleic acid or polypeptide sequences. The invention also provides for pharmaceutical compositions that include reoviruses having a modified sequence as well as methods of making and using such reoviruses.
Claims13
An isolated reovirus comprising a lambda-3 polypeptide, wherein the lambda-3 polypeptide comprises SEQ ID NO:19.
An isolated reovirus, said reovirus having IDAC Accession No. 190907-01.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:19.
Dependencies are inferred from the claim text.