Composition comprising double stranded RNA that inhibits expression of NEU3 and method for treating cancer
AssigneeMiyagi Ken
InventorsTaeko Miyagi, Tadashi Wada, Kazunori Yamaguchi
Life of this patent
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Abstract
A pharmaceutical composition for treating cancer or diabetes which contains the following double-stranded RNA (A) or (B): (A) a double-stranded RNA having a sequence represented by SEQ ID NO:2, SEQ ID NO:4 or SEQ ID NO:8. (B) a double-stranded RNA which has a sequence of 20 to 30 nucleotides that is identical to a partial sequence of a gene encoding human plasma membrane-associated sialidase (NEU3) and contains the sequence represented by SEQ ID NO: 2, SEQ ID NO: 4, or SEQ ID NO: 8, and the double-stranded RNA inhibits the expression of a gene encoding human plasma membrane-associated sialidase (NEU3).
Claims9
A composition comprising a double-stranded RNA shown in (A) or (B):
- (A) a double-stranded RNA wherein one strand is the sequence represented by SEQ ID NO:
- 2;
- (B) a double-stranded RNA which is 20 to 30 nucleotides in length and contains the sequence of SEQ ID NO:
- 2;
- wherein the double-stranded RNA inhibits the expression of a gene encoding human plasma membrane-associated sialidase (NEU3).
Dependencies are inferred from the claim text.