Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of the rspAB operon

A method for producing an L-amino acid comprising:

• I) cultivating an L-amino acid-producing Escherichia coli bacterium in a medium, and
• II) collecting said L-amino acid from the medium,
• wherein said bacterium has been modified to attenuate expression of the rspAB operon by a method selected from the group consisting of:
• A) deleting a part of the rspAB operon,
• B) shifting the reading frame of the rspAB operon,
• C) introducing one or more missense and/or nonsense mutations into the rspAB operon,
• D) modifying a region that is adjacent to the rspAB operon which controls gene expression, and
• E) combinations thereof;
• and
• wherein the rspAB operon comprises the rspA and rspB genes, and
• wherein the rspA and rspB genes encode proteins having at least 95% homology to the amino acid sequence of SEQ ID NO:
• 2 and SEQ ID NO:
• 4, respectively.