Enzyme inhibitors
AssigneesConsejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid (UAM)
InventorsAna Martinez Gil, Ana Castro Morera, Maria Concepcion Martin Perez, Mercedes Alonso Cascon, Isabel Dorronsoro Diaz, Francisco Jose Moreno Munoz, Francisco Wandosell Jurado
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Abstract
Compounds of general formula (I): where A, E, G, X, Y and the bond - - - take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arteriosclerosis or restenosis.
Claims10
A compound having formula (II):
- wherein
- Ra is benzyl;
- Rb is alkyl;
- and
- X and Y are both O;
- or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition comprising a compound having formula (II) or a pharmaceutically acceptable salt thereof:
- wherein
- Ra is benzyl;
- Rb is alkyl;
- and
- X and Y are both O;
- and a pharmaceutically acceptable carrier or diluent.
Dependencies are inferred from the claim text.