Arginine/lysine-enriched peptides
AssigneeCampina B.V.
InventorsAnita Dekker, Johanna Maria Henrica van der Steen
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Abstract
Described is a method for the preparation of a mixture of peptides, having an arginine and lysine content of at least 20 w/w %, based on the protein content, from at least one protein source, to a preparation comprising a mixture of arginine- and lysine-rich peptides, comprising at least 20 w/w % arginine and lysine, and to the use of the said preparation as active compound in a medicament, supplement, beverage or food product.
Claims10
A process for the preparation of a mixture of peptides by cationic exchange chromatography, having an arginine and lysine content of at least 20 w/w %, based on the total amount of protein, from at least one protein source, comprising the steps of:
- a) cleaving the proteins of at least one protein source into peptides;
- b) allowing the peptides to bind to cation exchange resin;
- c) washing the cation exchange resin with an alkaline wash solution having a hydroxide normality of 0.05-2.0;
- and
- d) eluting bound peptides from the resin with an aqueous elution solution having an ionic strength of at most 200 mM and a pH between 5.0-9.0.
Dependencies are inferred from the claim text.