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US 7,759,518 B2Granted
Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK
AssigneeArdea Biosciences, Inc.
InventorsAndreas Maderna, Jean-Michel Vernier, Dinesh Barawkar, Varaprasad Chamakura, Hassan el Abdellaoui, Zhi Hong
Life of this patent
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Abstract
This invention concerns N-(2-arylamino)aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.
Claims4
The compound (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide:
A pharmaceutical composition comprising a therapeutically effective amount of (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide:
Dependencies are inferred from the claim text.