# US 7,745,620 B2 · Disubstituted cucurbiturils and preparing method thereof

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- Number: US 7,745,620 B2
- Document ID: US7745620B2
- Status: Granted
- Kind: B2
- Application number: 10/598,861
- Filed: 2004-03-13
- Published: 2008-06-12
- Granted: 2010-06-29
- Earliest claimed: 2004-03-13
- Assignees: Postech Foundation
- Inventors: Kimoon Kim; Jae Wook Lee; Dong Hyun Oh; Jeongmin Ju
- Web page: https://patentgrep.com/patent/US7745620B2

## CPC

- C07D 487/22: in which the condensed system contains four or more hetero rings
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)

## Abstract

Provided are a disubstituted cucurbituril that can be easily substituted by a substituent according to a desired usage and a method for preparing the same. The disubstituted cucurbituril has two end functional groups that can covalently bind with a solid substrate or a biochemically useful compound to obtain a cucurbituril-bonded substrate, which enables application of the disubstituted cucurbituril as column packing materials for chromatography, additives to gas separation membranes, catalysts for various chemical reactions, chemical sensors, or biological sensors.

## Claims

### Claim 1

A disubstituted cucurbit[m]uril where m is 5 to 8, represented by the following Formula I:
wherein
n is an integer of 4 to 7;
X is O, S, or NH;
R is selected from the group consisting of a 2-nitrophenyl group, a 3-nitrophenyl group, a 4-nitrophenyl group, a 2-methoxyphenyl group, a 3-methoxyphenyl group, a 4-methoxyphenyl group, a 2-aminophenyl group, a 3-aminophenyl group, a 4-aminophenyl group, a 2-hydroxyphenyl group, a 3-hydroxyphenyl group, and a 4-hydroxyphenyl group.

### Claim 2 (depends on 1)

A column packing material for chromatography comprising the disubstituted cucurbit[m]uril of claim 1.