# US 7,745,496 B2 · Process for preparing halogenoalkylnitrates

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- Number: US 7,745,496 B2
- Document ID: US7745496B2
- Status: Granted
- Kind: B2
- Application number: 11/667,970
- Filed: 2005-11-09
- Published: 2008-01-03
- Granted: 2010-06-29
- Earliest claimed: 2004-11-25
- Assignees: Nicox S.A.
- Inventors: Romano Rivolta; Peter Finlander
- Web page: https://patentgrep.com/patent/US7745496B2

## CPC

- C07C 203/04: having nitrate groups bound to acyclic carbon atoms
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS

## Abstract

A process for preparing a compound of formula (I) X-(CH2)n-ONO2 (I) wherein: X is a halogen atom selected from Cl, Br, I; n is an integer from 3 to 6; said process comprising the slow addition of a compound of formula (II) X-(CH2)n-OH (II) wherein X and n are as defined above to a nitrating agent selected from the group consisting of concentrated nitric acid/concentrated sulfuric acid (sulfonitric mixture), nitric acid alone, NaNO2 in trifluoroacetic acid, nitronium salts such as NO2BF4 and an organic solvent selected from the group consisting of CH2Cl2, CHCl3, CCl4, perfluorohexane, perfluoroheptane. The invention refers also to solutions containing: a compound of general formula (I) and a solvent selected from the group consisting of CH2Cl2, CHCl3, CCl4, perfluorohexane, perfluoroheptane, characterized in that the compound of formula (I) is present in a concentration not higher than 20% by weight.

## Claims

### Claim 1

A solution containing:
a) a compound of general formula (I)
X-(CH2)n-ONO2 (I)
wherein:
X is a halogen atom selected from the group consisting of: Cl, Br, and I;
n is an integer from 3 to 6; and
b) a solvent selected from the group consisting of:
CH2Cl2, CHCl3, CCl4, perfluorohexane, and perfluoroheptane;
wherein the compound of formula (I) is present in a concentration not higher than 20% by weight.

### Claim 2 (depends on 1)

A solution according to claim 1 containing a compound of formula (I) wherein n is 4.

### Claim 3 (depends on 1)

A solution according to claim 1 containing a compound of formula (I) wherein X is Br.

### Claim 4 (depends on 1)

A solution according to claim 1 wherein the solvent is CH2Cl2.

### Claim 5 (depends on 1)

A solution according to claim 1 wherein the compound of formula (I) is present in a concentration from 10% to 20% by weight.

### Claim 6 (depends on 1)

A process for preparing a compound of formula (I) as defined in claim 1, said process comprising the slow addition of a compound of formula (II)
X-(CH2)n-OH (II)
wherein X and N are as defined in claim 1 to a nitrating agent selected from the group consisting of concentrated nitric acid/concentrated sulfuric acid (sulfonitric mixture), nitric acid alone, NaNO2 in trifluoroacetic acid, nitronium salts such as NO2BF4 and an organic solvent selected from the group consisting of CH2Cl2, CHCl3, CCl4, perfluorohexane, perfluoroheptane.

### Claim 7 (depends on 6)

A process according to claim 6 for preparing a compound of formula (I) wherein X is Br.

### Claim 8 (depends on 6)

A process according to claim 6 wherein the organic solvent is CH2Cl2.