# US 7,745,487 B2 · Method for enhancing physical performance or immune system recovery from intense physical excercise with quercetin-containing compositions

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- Number: US 7,745,487 B2
- Document ID: US7745487B2
- Status: Granted
- Kind: B2
- Application number: 11/778,237
- Filed: 2007-07-16
- Published: 2008-02-07
- Granted: 2010-06-29
- Earliest claimed: 2006-07-17
- Assignees: Quercegen Pharma LLC
- Inventors: Thomas Christian Lines
- Web page: https://patentgrep.com/patent/US7745487B2

## CPC

- C07D 213/80: in position 3
- A61K 31/352: condensed with carbocyclic rings, e.g. methantheline {(cannabinoids A61K31/658)}
- A61K 31/375: Ascorbic acid, i.e. vitamin C; Salts thereof
- A61K 31/445: Non condensed piperidines, e.g. piperocaine
- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61P 1/00: Drugs for disorders of the alimentary tract or the digestive system
- A61P 3/00: Drugs for disorders of the metabolism (of the blood or the extracellular fluid A61P7/00)
- A61P 3/10: for hyperglycaemia, e.g. antidiabetics
- A61P 9/00: Drugs for disorders of the cardiovascular system
- A61P 11/00: Drugs for disorders of the respiratory system
- A61P 15/00: Drugs for genital or sexual disorders (for disorders of sex hormones A61P5/24); Contraceptives
- A61P 17/00: Drugs for dermatological disorders
- A61P 19/02: for joint disorders, e.g. arthritis, arthrosis
- A61P 25/28: for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 31/00: Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P 31/04: Antibacterial agents
- A61P 31/12: Antivirals
- A61P 35/00: Antineoplastic agents
- A61P 37/00: Drugs for immunological or allergic disorders
- A61P 37/06: Immunosuppressants, e.g. drugs for graft rejection
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

This invention relates to a composition containing quercetin, vitamin B3, vitamin C, and folic acid. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.

## Claims

### Claim 1

A method for enhancing physical performance or immune system recovery from intense physical exercise, comprising administering to a subject in need thereof an effective amount of a composition containing quercetin, vitamin B3, vitamin C, and folic acid, wherein a weight ratio between the quercetin, the vitamin B3, and the vitamin C is 1:0.02-1:0.2-2.5.

### Claim 2 (depends on 1)

The method of claim 1, wherein the weight ratio is 1:0.05-0.2:0.5-1.

### Claim 3 (depends on 1)

The method of claim 1, wherein the weight ratio is 1:0.1-0.2:0.5-1.

### Claim 4 (depends on 1)

The method of claim 1, wherein the weight ratio is 1:0.04:1.

### Claim 5 (depends on 1)

The method of claim 1, wherein the weight ratio is 1:0.08:1.

### Claim 6 (depends on 1)

The method of claim 1, wherein the composition is in dry form.

### Claim 7 (depends on 1)

The method of claim 1, wherein the composition is in liquid form.

### Claim 8 (depends on 1)

The method of claim 1, wherein the composition is a food product selected from the group consisting of tea, soft drink, juice, milk, coffee, jelly, ice cream, yogurt, cookie, cereal, chocolate, and snack bar.

### Claim 9 (depends on 1)

The method of claim 1, wherein the composition is a dietary supplement or a pharmaceutical formulation.

### Claim 10 (depends on 9)

The method of claim 9, wherein the composition is a tablet, a capsule, a soft chew, or a gel.

### Claim 11 (depends on 1)

The method of claim 1, wherein the vitamin B3 is niacinamide.

### Claim 12 (depends on 1)

The method of claim 1, wherein the vitamin B3 is nicotinic acid.

### Claim 13 (depends on 1)

The method of claim 1, wherein the composition further contains an agent selected from the group consisting of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), epigallocatechin gallate (EGCG), genistein, genistin, isoquercetin, and a combination thereof.

### Claim 14 (depends on 13)

The method of claim 13, wherein the weight ratio is 1:0.05-0.2:0.5-1.

### Claim 15 (depends on 13)

The method of claim 13, wherein the weight ratio is 1:0.1-0.2:0.5-1.

### Claim 16 (depends on 13)

The method of claim 13, wherein the weight ratio is 1:0.04:1.

### Claim 17 (depends on 13)

The method of claim 13, wherein the weight ratio is 1:0.08:1.

### Claim 18 (depends on 13)

The method of claim 13, wherein the composition is in dry form.

### Claim 19 (depends on 13)

The method of claim 13, wherein the composition is in liquid form.

### Claim 20 (depends on 13)

The method of claim 13, wherein the composition is a food product selected from the group consisting of tea, soft drink, juice, milk, coffee, jelly, ice cream, yogurt, cookie, cereal, chocolate, and snack bar.

### Claim 21 (depends on 13)

The method of claim 13, wherein the composition is a dietary supplement or a pharmaceutical formulation.

### Claim 22 (depends on 21)

The method of claim 21, wherein the composition is a tablet, a capsule, a soft chew, or a gel.

### Claim 23 (depends on 13)

The method claim 13, wherein the vitamin B3 is niacinamide.

### Claim 24 (depends on 13)

The method of claim 13, wherein the vitamin B3 is nicotinic acid.

### Claim 25 (depends on 13)

The method of claim 13, wherein the agent is isoquercetin.

### Claim 26 (depends on 13)

The method of claim 13, wherein the agent is EGCG.

### Claim 27 (depends on 26)

The method of claim 26, wherein the agent is EPA or DHA.

### Claim 28 (depends on 1)

The method of claim 1, wherein the method is for enhancing physical performance.

### Claim 29 (depends on 28)

The method of claim 28, wherein the composition further contains an agent selected from the group consisting of DHA, EPA, EGCG, genistein, genistin, isoquercetin, and a combination thereof.

### Claim 30 (depends on 1)

The method of claim 1, wherein the method is for enhancing immune system recovery from intense physical exercise.

### Claim 31 (depends on 30)

The method of claim 30, wherein the composition further contains an agent selected from the group consisting of DHA, EPA, EGCG, genistein, genistin, isoquercetin, and a combination thereof.
