# US 7,745,486 B2 · Quercetin-containing compositions

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- Number: US 7,745,486 B2
- Document ID: US7745486B2
- Status: Granted
- Kind: B2
- Application number: 11/778,234
- Filed: 2007-07-16
- Published: 2008-01-17
- Granted: 2010-06-29
- Earliest claimed: 2006-07-17
- Assignees: Quercegen Pharma LLC
- Inventors: Thomas Christian Lines
- Web page: https://patentgrep.com/patent/US7745486B2

## CPC

- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61K 31/352: condensed with carbocyclic rings, e.g. methantheline {(cannabinoids A61K31/658)}
- A61K 31/375: Ascorbic acid, i.e. vitamin C; Salts thereof
- A61K 31/455: Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
- A61P 1/00: Drugs for disorders of the alimentary tract or the digestive system
- A61P 1/10: Laxatives
- A61P 3/04: Anorexiants; Antiobesity agents
- A61P 3/06: Antihyperlipidemics
- A61P 3/10: for hyperglycaemia, e.g. antidiabetics
- A61P 9/00: Drugs for disorders of the cardiovascular system
- A61P 9/10: for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A61P 11/00: Drugs for disorders of the respiratory system
- A61P 13/08: of the prostate
- A61P 15/00: Drugs for genital or sexual disorders (for disorders of sex hormones A61P5/24); Contraceptives
- A61P 15/08: for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A61P 17/00: Drugs for dermatological disorders
- A61P 19/02: for joint disorders, e.g. arthritis, arthrosis
- A61P 25/00: Drugs for disorders of the nervous system
- A61P 25/28: for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A61P 31/00: Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P 31/04: Antibacterial agents
- A61P 31/12: Antivirals
- A61P 31/16: for influenza or rhinoviruses
- A61P 35/00: Antineoplastic agents
- A61P 35/02: specific for leukemia
- A61P 37/00: Drugs for immunological or allergic disorders
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C07D 213/80: in position 3
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)

## Abstract

This invention relates to a composition containing quercetin, vitamin B3, and vitamin C. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.

## Claims

### Claim 1

A composition comprising quercetin, vitamin B3, and vitamin C as the only active ingredients, wherein a weight ratio between the quercetin, the vitamin B3, and the vitamin C is 1:0.02-1:0.2-2.5.

### Claim 2 (depends on 1)

The composition of claim 1, wherein the weight ratio is 1:0.05-0.2:0.5-1.

### Claim 3 (depends on 1)

The composition of claim 1, wherein the weight ratio is 1:0.1-0.2:0.5-1.

### Claim 4 (depends on 1)

The composition of claim 1, wherein the weight ratio is 1:0.04:1.

### Claim 5 (depends on 1)

The composition of claim 1, wherein the weight ratio is 1:0.08:1.

### Claim 6 (depends on 1)

The composition of claim 1, wherein the composition is in dry form.

### Claim 7 (depends on 1)

The composition of claim 1, wherein the composition is in liquid form.

### Claim 8 (depends on 1)

The composition of claim 1, wherein the composition is a food product selected from the group consisting of tea, soft drink, juice, milk, coffee, jelly, ice cream, yogurt, cookie, cereal, chocolate, and snack bar.

### Claim 9 (depends on 8)

The composition of claim 8, wherein the food product is tea, soft drink, juice, or snack bar.

### Claim 10 (depends on 1)

The composition of claim 1, wherein the composition is a dietary supplement or a pharmaceutical formulation.

### Claim 11 (depends on 10)

The composition of claim 10, wherein the composition is a tablet, a capsule, a soft chew, or a gel.

### Claim 12 (depends on 1)

The composition of claim 1, wherein the vitamin B3 is niacinamide.

### Claim 13 (depends on 1)

The composition of claim 1, wherein the vitamin B3 is nicotinic acid.

### Claim 14

A composition comprising quercetin, vitamin B3, vitamin C, and another agent as the only active ingredients, wherein a weight ratio between the quercetin, the vitamin B3, and the vitamin C is 1:0.02-1:0.2-2.5, and the other agent is selected from the group consisting of genistein, genistin, curcumin, reserveratrol, isoquercetin, epigallocatechin gallate (EGCG), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and a combination thereof.

### Claim 15 (depends on 14)

The composition of claim 14, wherein the other agent is a combination of isoquercetin, EGCG, EPA, and DHA.

### Claim 16 (depends on 14)

The composition of claim 14, wherein the weight ratio is 1:0.05-0.2:0.5-1.

### Claim 17 (depends on 14)

The composition of claim 14, wherein the weight ratio is 1:0.1-0.2:0.5-1.

### Claim 18 (depends on 14)

The composition of claim 14, wherein the weight ratio is 1:0.04:1.

### Claim 19 (depends on 14)

The composition of claim 14, wherein the weight ratio is 1:0.08:1.

### Claim 20 (depends on 14)

The composition of claim 14, wherein the composition is in dry form.

### Claim 21 (depends on 14)

The composition of claim 14, wherein the composition is in liquid form.

### Claim 22 (depends on 14)

The composition of claim 14, wherein the composition is a food product selected from the group consisting of tea, soft drink, juice, milk, coffee, jelly, ice cream, yogurt, cookie, cereal, chocolate, and snack bar.

### Claim 23 (depends on 14)

The composition of claim 14, wherein the vitamin B3 is niacinamide.

### Claim 24 (depends on 14)

The composition of claim 14, wherein the vitamin B3 is nicotinic acid.

### Claim 25 (depends on 14)

The composition of claim 14, wherein the composition is a dietary supplement or a pharmaceutical formulation.

### Claim 26 (depends on 25)

The composition of claim 25, wherein the composition is a tablet, a capsule, a soft chew, or a gel.
