# US 7,745,227 B2 · System for analysis of explosives

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 7,745,227 B2
- Document ID: US7745227B2
- Status: Granted
- Kind: B2
- Application number: 10/915,973
- Filed: 2004-08-11
- Published: 2005-03-24
- Granted: 2010-06-29
- Earliest claimed: 2003-08-12
- Assignees: Lawrence Livermore National Security, LLC
- Inventors: Jeffrey S. Haas
- Web page: https://patentgrep.com/patent/US7745227B2

## CPC

- G01N 30/94: Development
- G01N 30/90: Plate chromatography, e.g. thin layer or paper chromatography
- G01N 33/22: Fuels; Explosives
- G01N 2030/625: {by measuring reference material, e.g. carrier without sample}
- Y10T 436/172307: Cyanide or isocyanide
- Y10T 436/173076: Nitrite or nitrate
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

A system for analysis of explosives. Samples are spotted on a thin layer chromatography plate. Multi-component explosives standards are spotted on the thin layer chromatography plate. The thin layer chromatography plate is dipped in a solvent mixture and chromatography is allowed to proceed. The thin layer chromatography plate is dipped in reagent 1. The thin layer chromatography plate is heated. The thin layer chromatography plate is dipped in reagent 2.

## Claims

### Claim 1

A method for analyzing samples for
explosives, comprising the steps of:
providing a thin layer chromatography plate,
providing a tank,
providing a solvent mixture,
providing a reagent 1,
providing a reagent 2, and
performing the following combination of steps in the following order:
Step 1, mark locations for the samples on said thin layer chromatography plate,
Step 2, spot samples on said thin layer chromatography plate at said locations,
Step 3, spot multi-component explosives standards on said thin layer chromatography plate at said locations,
Step 4, add said solvent mixture to said tank,
wherein said solvent mixture is formulated as follows: 80 ml hexane+10 ml isopropanol+3 ml N,N-dimethylformamide+5 ml p-xylene+5 ml of methoxyethanol,
Step 5, dip said thin layer chromatography plate in said solvent mixture and allow chromatography to proceed,
Step 6, dip said thin layer chromatography plate in said reagent I and monitor for color to indicate explosives,
Step 7, heat said thin layer chromatography plate, and
Step 8, dip said thin layer chromatography plate in said reagent 2 and monitor for color to indicate explosives.

### Claim 2

A method for analyzing samples for
explosives, comprising the steps of:
providing a thin layer chromatography plate,
providing a tank,
providing a solvent mixture,
providing a reagent 1,
providing a reagent 2, and
performing the following combination of steps in the following order:
Step 1, mark locations for the samples on said thin layer chromatography plate,
Step 2, spot samples on said thin layer chromatography plate at said locations,
Step 3, spot multi-component explosives standards on said thin layer chromatography plate at said locations,
Step 4, add said solvent mixture to said tank,
Step 5, dip said thin layer chromatography plate in said solvent mixture and allow chromatography to proceed,
Step 6, dip said thin layer chromatography plate in said reagent I and monitor for color to indicate explosives,
wherein Step 6 of dipping said thin layer chromatography plate in reagent I comprises dipping said thin layer chromatography plate in reagent I formulated as follows: 10 ml of tetra-butylammonium hydroxide 40% in water, i.e., 1.5N is added to 90 ml of an iso-propanol/water (50:50) mixture, and adding 0.5 grams of sodium hydroxide to that mixture,
Step 7, heat said thin layer chromatography plate, and Step 8, dip said thin layer chromatography plate in said reagent 2, and monitor for color to indicate explosives,
Step 8, dip said thin layer chromatography plate in said reagent 2 and monitor for color to indicate explosives.