# US 7,744,610 B2 · System for closing a tissue structure from inside

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- Number: US 7,744,610 B2
- Document ID: US7744610B2
- Status: Granted
- Kind: B2
- Application number: 11/780,648
- Filed: 2007-07-20
- Published: 2008-01-24
- Granted: 2010-06-29
- Earliest claimed: 2005-03-28
- Assignees: Cardica, Inc.
- Inventors: Bernard A. Hausen
- Web page: https://patentgrep.com/patent/US7744610B2

## CPC

- A61B 17/0684: {having a forming anvil staying above the tissue during stapling}
- A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)}
- A61B 17/0644: {penetrating the tissue, deformable to closed position}
- A61B 17/10: for applying or removing wound clamps {, e.g. containing only one clamp or staple (A61B17/076 takes precedence; containing multiple wound clamps A61B17/068)}; Wound clamp magazines
- A61B 2017/00243: {cardiac}
- A61B 2017/00637: {for sealing trocar wounds through abdominal wall}
- A61B 2017/00668: {the implement being a tack or a staple}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A method for closing an aneurysm in a blood vessel may utilize a staple having two or more tines, where those tines are oriented at least partially in the proximal direction. The method may include advancing the staple through the vasculature to a location within the aneurysm, plastically deforming the staple to a splayed configuration, penetrating at least one said tine of the staple in that splayed configuration into tissue in proximity to the neck of the aneurysm, and plastically deforming the staple to a closed configuration to close the aneurysm.

## Claims

### Claim 1

A method for closing an aneurysm, the aneurysm having a neck connected to a blood vessel, comprising:
providing a staple having a plurality of tines, said tines oriented at least partially in the proximal direction;
advancing said staple through the vasculature to a location within the aneurysm;
plastically deforming said staple to a splayed configuration;
penetrating at least one said tine of said staple in said splayed configuration into tissue in proximity to the neck of the aneurysm
plastically deforming said staple to a closed configuration, whereby the neck of the aneurysm is substantially closed; and providing an end effector, wherein said end effector holds said staple; and wherein said plastically deforming said staple to a splayed configuration and said plastically deforming said staple to a closed configuration are performed by said end effector.

### Claim 2 (depends on 1)

The method of claim 1, further comprising
providing a guidewire; and
advancing said guidewire through the vasculature until the distal end of said guidewire is located within the aneurysm;
wherein said advancing said staple is performed by advancing said end effector along said guidewire.

### Claim 3 (depends on 2)

The method of claim 2, wherein said penetrating is caused by moving said staple proximally along said guidewire.

### Claim 4 (depends on 1)

The method of claim 1, wherein said advancing comprises advancing said staple through the vasculature to a location completely within the aneurysm.

### Claim 5 (depends on 1)

The method of claim 1, wherein said end effector includes a housing, further comprising passively ejecting said staple from said housing after said plastically deforming said staple to a closed configuration.

### Claim 6 (depends on 5)

The method of claim 5, further comprising holding said staple completely within said housing before said plastically deforming said staple to said splayed configuration.

### Claim 7 (depends on 1)

The method of claim 1, wherein said advancing is performed without a guidewire.