# US 7,744,566 B2 · System of infusion of pharmacological solutions > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 7,744,566 B2 - Document ID: US7744566B2 - Status: Granted - Kind: B2 - Application number: 10/563,909 - Filed: 2004-07-09 - Published: 2006-07-27 - Granted: 2010-06-29 - Earliest claimed: 2003-07-11 - Assignees: H.S. Hospital Services S.p.A. - Inventors: Marco Pirovano; Stefania Improta - Web page: https://patentgrep.com/patent/US7744566B2 ## CPC - A61M 5/152: pressurised by contraction of elastic reservoirs - A61M 5/16881: {Regulating valves} - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A system for the infusion of pharmacological solutions includes a container to contain a pharmacological solution, a pumping device for generating a flow of pharmacological solution from the container, an adjusting device to vary the flow and a command and control device operationally associated with the adjusting device. A method for the infusion of a pharmacological solution in a patient includes generating a flow of pharmacological solution from a container containing the pharmacological solution, sending the flow to a catheter insertable in the patient, adjusting the flow by an adjusting device actuated by a command and control device, and programming the flow and infusion times using a programming device operationally connected to the command and control device. ## Claims ### Claim 1 A system for the infusion of a pharmacological solution in a patient, comprising: an elastomeric container for containing a pharmacological solution and for generating a flow of the pharmacological solution from said container to a catheter insertable in the body of the patient, said elastomeric container, in use, exerting a pressure on the pharmacological solution that generates the flow; a valve arrangement to vary the flow; a command and control device operationally connected to said valve arrangement to command a pulsed actuation of said valve arrangement, the flow being determined by the number of actuations of said valve arrangement per unit time; an infusion protocol according to which the pulsed actuation is made, said infusion protocol being stored on a data-processing system or on a data-storage support, said stored infusion protocol being not modifiable; and said stored infusion protocol including at least an infusion curve, said infusion curve being defined by definition parameters comprising a duration of infusion, a volume of pharmacological solution to be infused, and a type of the infusion curve, wherein a number, a duration and a distribution of opening cycles of said valve arrangement are calculated to plot said infusion curve. ### Claim 2 (depends on 1) The system according to claim 1, wherein said valve arrangement comprises a valve of the normally closed type. ### Claim 3 (depends on 1) The system according to claim 1, wherein said valve arrangement comprises at least one solenoid valve. ### Claim 4 (depends on 1) The system according to claim 1, wherein said command and control device comprises a microprocessor operationally connected to said valve arrangement. ### Claim 5 (depends on 1) The system according to claim 1, wherein said elastomeric container is supported on a support element associated with a containing and protection element. ### Claim 6 (depends on 5) The system according to claim 5, wherein said containing and protection element is made of transparent material and is equipped on its outside surface with a graduated scale. ### Claim 7 (depends on 5) The system according to claim 5, wherein said containing and protection element comprises an inlet portion connected to said elastomeric container to introduce therein the pharmacological solution. ### Claim 8 (depends on 7) The system according to claim 7, wherein said inlet portion is associated with a connecting element suitable for enabling coupling of said inlet portion with an introducing device, to introduce the pharmacological solution into said inlet portion. ### Claim 9 (depends on 7) The system according to claim 7, wherein said containing and protection element furthermore comprises an outlet portion connected to said elastomeric container, through which the pharmacological solution introduced into the elastomeric container can flow out thereof. ### Claim 10 (depends on 9) The system according to claim 9, wherein said outlet portion is suitable for being connected to a first end of a fitting element, a second end of which is connected to said valve arrangement. ### Claim 11 (depends on 10) The system according claim 10, wherein said valve arrangement is associated with a further connecting element suitable for enabling coupling of said valve arrangement with a delivery device, for administration of the pharmacological solution. ### Claim 12 (depends on 1) The system according to claim 1, comprising an interface element for operationally connecting said command and control device with said data processing system. ### Claim 13 (depends on 1) The system according to claim 1, wherein said command and control device comprises a reading device suitable for receiving a data recording support and for reading data stored thereupon. ### Claim 14 (depends on 13) The system according to claim 13, wherein said data recording support is a data recording support of the smart-card type. ### Claim 15 (depends on 1) The system according to claim 1, comprising a battery to supply power to said command and control device. ### Claim 16 (depends on 15) The system according to claim 15, wherein said battery is of the rechargeable or replaceable type. ### Claim 17 (depends on 1) The system according to claim 1, wherein said command and control device comprises a microprocessor operationally connected to said valve arrangement, said infusion protocol being stored in said microprocessor. ### Claim 18 (depends on 1) The system according to claim 1, wherein the elastomeric container is structured or configured to exert a pressure on the pharmacological solution that has a substantially constant value.