Minimizing hemodynamic compromise during post-mi remodeling control pacing
AssigneeCardiac Pacemakers, Inc.
InventorsJoseph M. Pastore, Rodney W. Salo, Jesse W. Hartley, Andrew P. Kramer, Jeffrey E. Stahmann
Life of this patent
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Abstract
A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an assessment of cardiac function in order to balance the beneficial effects of stress reduction with hemodynamic compromise.
Claims18
An implantable device for delivering cardiac therapy to a patient, comprising:
- one or more pacing channels for delivering pacing pulses to one or more ventricular sites;
- a sensor for measuring a parameter related to cardiac function;
- a controller for controlling the delivery of pacing pulses to one or more ventricular sites during a cardiac cycle in accordance with a programmed pacing mode;
- wherein the controller is programmed to deliver pre-excitation pacing which pre-excites a region of the ventricular myocardium so as to mechanically unload that region during systole;
- and,
- wherein the controller is further programmed to derive a cardiac function assessment from the measured cardiac function parameter and modulate the amount of pre-excitation pacing in accordance therewith, wherein the controller is programmed to reduce the amount of pre-excitation pacing if the cardiac function assessment is below a specified threshold value.
A method for delivering cardiac therapy to a patient, comprising:
- delivering pacing pulses to one or more ventricular sites as pre-excitation pacing which pre-excites a region of the ventricular myocardium so as to mechanically unload that region during systole;
- measuring a parameter related to cardiac function;
- and,
- deriving a cardiac function assessment from the measured cardiac function parameter and modulate the amount of pre-excitation pacing in accordance therewith by reducing the amount of pre-excitation pacing if the cardiac function assessment is below a specified threshold value.
An implantable device for delivering cardiac therapy to a patient, comprising:
- one or more pacing channels for delivering pacing pulses to one or more ventricular sites;
- a sensor for measuring a parameter related to cardiac function;
- a controller for controlling the delivery of pacing pulses to one or more ventricular sites during a cardiac cycle in accordance with a programmed pacing mode;
- wherein the controller is programmed to deliver pre-excitation pacing which pre-excites a region of the ventricular myocardium so as to mechanically unload that region during systole;
- and,
- wherein the controller is further programmed to derive a cardiac function assessment from the measured cardiac function parameter and modulate the amount of pre-excitation pacing in accordance therewith, wherein the controller is programmed to maintain within a specified range a ratio of cardiac function to pre-excitation pacing.
A method for delivering cardiac therapy to a patient, comprising:
- delivering pacing pulses to one or more ventricular sites as pre-excitation pacing which pre-excites a region of the ventricular myocardium so as to mechanically unload that region during systole;
- measuring a parameter related to cardiac function;
- and,
- deriving a cardiac function assessment from the measured cardiac function parameter and modulating the amount of pre-excitation pacing in accordance therewith by maintaining within a specified range a ratio of cardiac function to pre-excitation pacing.
Dependencies are inferred from the claim text.