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US 7,741,624 B1Granted
Single session interactive ultra-short duration super-high biological dose rate radiation therapy and radiosurgery
OwnerVelayudhan Sahadevaninventor
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OwnerVelayudhan Sahadevaninventor
Estimating the term…
A medical accelerator system consisting of coplanar and non-coplanar beams, on line magnetic resonance anatomic and functional imaging and cone beam computed tomographic imaging for single session image guided all field simultaneous radiation therapy and radiosurgery is provided. This system enables single session simulation, field-shaping block making, treatment planning, dose calculations and treatment of tumors. The radiation exposure time to the tumor and the normal tissue is reduced to a few seconds to less than a minute. In filed intensity modulated radiation is rendered by combined divergent and pencil beam, multiple smaller fields within a larger field, selectively varying beam's energy, dose rate and beam weight. Since all the treatment fields are treated simultaneously the dose rate at the tumor site is the sum of each of the converging beam's dose rate at depth. This super-high biological dose rate impairs the lethal and sublethal damage repair.
A medical accelerator system for computerized tomography and magnetic resonance image guided radiation therapy and radiosurgery, wherein said radiation is rendered simultaneously to all treatment fields within a few seconds to less than a minute as intensity modulated radiation therapy with combined divergent and pencil beams or divergent or pencil beam alone.
A medical accelerator system equipped with magnetic resonance image and computerized tomography for image-guided simultaneous coplanar and non-coplanar beam radiation therapy and radiosurgery that last only a few seconds to less than a minute radiation exposure to a tumor, wherein said radiation exposure is a super-high biological dose rate of about 1000-4000 cGy that inhibits lethal and sublethal damage repair, thereby bringing the relative biological effectiveness of photon and electron radiation closer to that of high Linear Energy Transfer radiation like that of proton and neutron.
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