Antibodies to GM-CSF
AssigneeMorphotek, Inc.
InventorsPhilip M. Sass, Nicholas C. Nicolaides, Luigi Grasso, Jian Li, Qimin Chao, Eric Routhier, Wolfgang Ebel
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Abstract
Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.
Claims6
An isolated human monoclonal antibody that specifically binds to human GM-CSF wherein the heavy chain comprises the amino acid sequence of SEQ ID NO:
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Dependencies are inferred from the claim text.