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US 7,741,369 B2Granted
Lipoxin compounds and their use in treating cell proliferative disorders
AssigneeThe Brigham and Women's Hospital, Inc.
InventorCharles N. Serhan
Life of this patent
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Abstract
Compounds having the active site of natural lipoxins, but a longer tissue half-life are disclosed. In particular, 15-epi-lipoxins and their use in ameliorating undesired cell proliferation, which characterizes diseases such as cancer, are also disclosed.
Claims10
A method of inducing vasodilation to treat or prevent a vasocontractive response or condition, comprising:
- administering to a subject a pharmaceutical composition that includes a substantially purified 15-epi-lipoxin compound in which the absolute configuration at the 15 carbon is R and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.