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US 7,741,360 B2Granted
Bi-aryl or aryl-heteroaryl substituted indoles
AssigneeAstraZeneca AB
InventorsRoger Victor Bonnert, Timothy Jon Luker, John Cumming
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Abstract
The present invention relates to substituted indoles of Formula (I) useful as pharmaceutical compounds for treating respiratory disorders.
Claims15
A compound of formula (I) or a pharmaceutically acceptable salt thereof:
- in which
- X is O or S;
- R1 is NHCOR6;
- R2 is hydrogen, halogen, or C1-7alkyl;
- R3 is phenyl, which is substituted by phenyl;
- or phenyl, which is substituted by a 5-membered heteroaryl group;
- R6 is a hydrogen atom, or C1-6alkyl;
- Provided that:
- R3 cannot be 4-phenyl-1,3-thiazol-2-yl.
6 more elements
Dependencies are inferred from the claim text.