Use of tyrosine kinase inhibitors for treating inflammatory diseases
AssigneeScience Incorporated
InventorsAlain Moussy, Jean Pierre Kinet
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Abstract
The present invention relates to a method for treating inflammatory diseases such as rheumatoid arthritis (RA), comprising administering a tyrosine kinase inhibitor to a human in need of such treatment, more particularly a non-toxic, selective and potent c-kit inhibitor. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.
Claims1
A method for treating inflammatory diseases selected from the group consisting of rheumatoid arthritis, conjunctivitis, rheumatoid spondylitis, osteoarthritis, gouty arthritis, and polyarthritis, said method comprising administering an effective amount of the following compound:
- N-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide to a mammal in need of such treatment.
Dependencies are inferred from the claim text.