Low dose therapy for treating viral infections
AssigneeAchillion Pharmaceuticals, Inc.
InventorJohn Pottage
Life of this patent
Estimating the term…
Loading patent…
AssigneeAchillion Pharmaceuticals, Inc.
InventorJohn Pottage
Estimating the term…
A method of treating viral infections, particularly Hepatitis B (HBV) and Human Immunodeficiency Virus (HIV), by administering a low dose of Elvucitabine to a patient suffering viral infection is provided herein. The Elvucitabine dosages provided herein for effective anti-viral therapy are approximately 10-fold less than the effective dosages of currently marketed reverse transcriptase inhibitors. The Elvucitabine dosage may be given BID, daily, once every 48 hours, or once weekly. Also provided herein are packaged pharmaceutical formulations comprising Elvucitabine and instructions for treating a viral infection by administering a low BID, daily, once/48 hour, or weekly dosage of Elvucitabine. The low dose Elvucitabine formulations provided herein have the additional benefit of improving patient compliance with anti-viral therapy.
A method of treating a retrovirus infection comprising administering about 5 mg to about 20 mg Elvucitabine once per 48 hour interval or about 40 to 100 mg optically active Elvuctiabine once per one week interval to a human patient suffering from a retrovirus infection.
Dependencies are inferred from the claim text.