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US 7,741,326 B2Granted
Indole and benzofuran 2-carboxamide derivatives and uses thereof
AssigneeRoche Palo Alto LLC
InventorsJoe Timothy Bamberg, Counde O'Yang, Meng Sui, Shu-Hai Zhao
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Abstract
Compounds of formula I or formula II: or pharmaceutically acceptable salts thereof, wherein m, n, p, Ar R1, R2, R4, and R5 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds.
Claims5
A method for enhancing cognitive memory in an Alzheimer's patient, said method comprising administering to said Alzheimer's patient a therapeutically effective amount of a compound of formula III:
- wherein:
- s is 0 or 1;
- m is 0 or 1;
- Y is N;
- R1 is hydrogen or methyl;
- R2 is halo or C1-6alkyl;
- R8 is halo, C1-6alkyl, halo-C1-6alkoxy, C1-6alkoxy or cyano;
- and
- Re and Rf each independently is hydrogen or methyl.
6 more elements
Dependencies are inferred from the claim text.