Composition and method for treating occlusive vascular diseases, nerve regeneration, and wound healing
OwnerShaker Mousa, Robert Linhardtinventors
Life of this patent
Estimating the term…
Abstract
A composition and a method of treating a subject with respect to a pathological condition comprised by the subject. The composition comprises a sulfated saccharide conjugated to a polymer. The method comprises administering to the subject a composition comprising a sulfated saccharide conjugated to a polymer or a sulfated saccharide. The sulfated saccharide has a molecular weight less than 5000 Dalton.
Claims57
A composition, comprising a branched sulfated saccharide conjugated to a polymer, said sulfated saccharide having a molecular weight less than 5000 Dalton, said composition configured to be administered to a subject for treating the subject with the sulfated saccharide with respect to a pathological condition comprised by the subject, wherein the sulfated saccharide is conjugated to the polymer by being non-covalently bonded to the polymer, and wherein the sulfated saccharide that is non-covalently bonded to the polymer is encapsulated within a nano-particle haying a linear dimension less than 200 nanometers.
A composition, comprising a branched sulfated saccharide conjugated to a polymer, said sulfated saccharide having a molecular weight less than 5000 Dalton, said composition configured to be administered to a subject for treating the subject with the sulfated saccharide with respect to a pathological condition comprised by the subject, wherein the composition further comprises a pro-angiogenesis factor, a vasodilator, an agent, and combinations thereof, and wherein the agent selected from the group consisting of a neuro-protective agent, a memory enhancer, a nerve cell regeneration agent, and combinations thereof.
A composition, comprising a branched sulfated saccharide conjugated to a polymer, said sulfated saccharide having a molecular weight less than 5000 Dalton, said composition configured to be administered to a subject for treating the subject with the sulfated saccharide with respect to a pathological condition comprised by the subject, wherein the sulfated saccharide is conjugated to the polymer by being non-covalently bonded to the polymer, and wherein the sulfated saccharide is non-covalently bonded to the polymer by being entrapped in a polylactic acid (PLA) polymer.
A composition, comprising a branched sulfated saccharide conjugated to a polymer, said sulfated saccharide having a molecular weight less than 5000 Dalton, said composition configured to be administered to a subject for treating the subject with the sulfated saccharide with respect to a pathological condition comprised by the subject, wherein the polymer is polyethylene glycol (PEG).
Dependencies are inferred from the claim text.