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US 7,741,101 B2Granted
Escherichia strain capable of converting XMP to GMP and maintaining the inactivated state of gene(s) associated with GMP degradation and methods of using the same
AssigneeCj Cheiljedang Corporation
InventorsYoung-hoon Park, Hyoung-suk Kim, Jin-nam Lee, Ko-hoon Oh, Jeong-hwan Kim, Yoon-suk Oh, Jae-ick Sim, Kyung-oh Choi
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Abstract
Provided are mutant strains derived from Escherichia sp. GPU1114 (Accession No. KCCM-10536), having cumulative inactivation of deoD, aphA, appA, and hprt genes, and methods of using the same.
Claims10
An isolated strain of the genus Escherichia obtained by inactivation of the endogenous deoD, aphA, and appA genes of the strain Escherichia sp. GPU1114 deposited with Korean Culture Center of Microorganisms (KCCM) as Accession No. KCCM-10536, wherein said inactivation is by homologous recombination-based substitution.
Dependencies are inferred from the claim text.