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US 7,741,094 B2Granted
Protein having prolyl oligopeptidase activity, and composition containing the same
AssigneeFood Industry Research and Development Institute
InventorsJen-Tao Chen, Mei-Li Chao, Chiou-Yen Wen, Wen-Shen Chu
Life of this patent
Estimating the term…
Abstract
A protein of amino acid sequence SEQ ID NO:6 isolated from Coprinus clastophyllus. The protein is stable at 30 to 37 degrees centigrade and has an optimal prolyl oligopeptidase activity at about 45 degree centigrade and at about pH 7. The present invention also relates to a medicament comprising such protein for treating celiac disease caused by proline abundant gluten.
Claims4
An isolated protein selected from the group consisting of:
- (a) a protein comprising the amino acid sequence of SEQ ID NO:6;
- (b) a protein encoded by a nucleic acid comprising the sequence of SEQ ID NO:5, wherein said protein has prolyl oligopeptidase activity.
Dependencies are inferred from the claim text.