Methods and compositions for detecting spermatozoa or semen in a sample
AssigneeThe Curators of the University of Missouri
InventorsPeter Sutovsky, Antonio Miranda-Vizuete
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Abstract
The present invention concerns compositions and methods for evaluating fertility in humans and animals. The invention may also be used to identify reproductive cancers such as testicular cancer. In various embodiments of the invention, an Sptrx-3 enzyme is used as a fertility marker. Sptrx-3 may be detected in accordance with the invention in vitro or in vivo.
Claims9
A method of detecting spermatozoa or semen in a sample comprising assaying a sample for the presence of spermatid-specific thioredoxin-3 (Sptrx-3) or a nucleic acid sequence encoding Sptrx-3 according to SEQ ID NO :9, wherein the presence of the Sptrx-3 or nucleic acid sequence is indicative of the presence of spermatozoa or semen in the sample.
Dependencies are inferred from the claim text.