Methods and compositions for evaluating graft survival in a solid organ transplant recipient
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsMinnie M. Sarwal, Elaine S. Mansfield
Life of this patent
Estimating the term…
Abstract
Methods are provided for evaluating a subject for graft survival, e.g., in terms of predicting graft survival, identifying the presence of a deleterious graft condition, such as CAN and DT, identifying the severity and class of acute rejection, etc, in a subject are provided. In practicing the subject methods, the expression of at least one gene in a sample from the subject, e.g., a blood or biopsy sample, is assayed, e.g., at the nucleic acid and/or protein level, to evaluate the subject. Also provided are compositions, systems and kits that find use in practicing the subject methods. The methods and compositions find use in a variety of applications.
Claims15
A method of evaluating graft survival in a subject, said method comprising:
- assessing expression of at least two genes in a sample from said subject to evaluate graft survival in said subject, wherein said at least two genes comprises HIST1H2B and IGHG3.
Dependencies are inferred from the claim text.