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AssigneeUniversity of Utah Research Foundation
InventorsSung Wan Kim, Seongbong Jo, Jin Kim
Estimating the term…
A thermogelling, aliphatically modified polymer for use in drug delivery is described. Illustrative embodiments include poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) hexanoate and poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) laurate. Another illustrative embodiment includes a composition having a thermogelling amount of an aliphatically modified poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) and an effective amount of a drug. The thermogelling polymers are made by bonding an aliphatic group to poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone). A method of use includes injecting a warm-blooded individual with a thermogelling amount of the aliphatically modified polymer and a drug.
A composition of matter comprising poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) covalently bonded to at least one aliphatic hydrocarbon.
A composition of matter comprising a mixture of an effective amount of a drug and a thermogelling amount of poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) covalently bonded to an aliphatic hydrocarbon.
A method of forming a depot for time release of a drug, the method comprising injecting a warm-blooded individual with a composition of matter comprising a mixture of an effective amount of a drug and a thermogelling amount of poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) covalently bonded to an aliphatic hydrocarbon.
Dependencies are inferred from the claim text.