Group B Streptococcus antigens and corresponding DNA fragments
AssigneeID Biomedical Corporation
InventorsDenis Martin, Stéphane Rioux, Bernard R. Brodeur, Josée Hamel, Martine Boyer
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Abstract
The present invention relates to antigens, more particularly antigens of Group B Streptococcus (GBS) (S. agalactiae) which may be useful to prevent, diagnose and/or treat streptococcal infections.
Claims12
An isolated polypeptide comprising a polypeptide fragment, wherein the polypeptide fragment comprises at least 15 contiguous amino acids of a polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:2, wherein the polypeptide fragment is capable of eliciting antibodies that specifically bind to the polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:2.
A chimeric polypeptide comprising (a) two or more polypeptide fragments, wherein the two or more polypeptide fragments each comprise at least 15 contiguous amino acids of a polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:
- 2;
- provided that the two or more polypeptide fragments are linked to form a chimeric polypeptide, wherein the two or more polypeptide fragments are capable of eliciting antibodies that specifically bind to the polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:2.
Dependencies are inferred from the claim text.