Vaccines for diseases of fish
AssigneeUniversity of Idaho
InventorsKenneth D. Cain, Benjamin R. LaFrentz, Scott LaPatra
Life of this patent
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Abstract
Fish are immunized by a mass vaccination method, such as by immersion in water containing an attenuated strain of a pathogenic bacterium that does not effectively cause disease in fish when the non-attenuated pathogenic bacterium is exposed to the fish by immersion. An illustrative example of the method is for immunizing against coldwater disease caused by Flavobacterium psychrophilum, which may be attenuated by serial passage in media containing increasing amounts of an antibiotic, such as rifampicin.
Claims10
A vaccine for protecting non-wounded fish against a disease caused by non-attenuated Flavobacterium psychrophilum comprising isolated, live attenuated, rifampicin-resistant Flavobacterium psychrophilum, wherein when the non-wounded fish are exposed by immersion to a sufficient amount of the live attenuated, rifampicin-resistant Flavobacterium psychrophilum in the vaccine, the vaccine provides protection against the disease in the non-wounded fish.
An isolated, live attenuated, rifampicin-resistant Flavobacterium psychrophilum, which protects non-wounded fish from disease caused by non-attenuated Flavobacterium psychrophilum when the non-wounded fish are exposed by immersion to the live attenuated, rifampicin-resistant Flavobacterium psychrophilum.
A method of protecting non-wounded fish against disease caused by non-attenuated Flavobacterium psychrophilum comprising administering to the fish by mass immersion an amount of an isolated, live attenuated, rifampicin-resistant Flavobacterium psychrophilum sufficient to provide protection to the non-wounded fish against the disease.
Dependencies are inferred from the claim text.