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US 7,740,862 B2Granted
FSH mutants
AssigneeMerck Serono SA
InventorsMarco Muda, Xuliang Jiang, Sean D. McKenna
Life of this patent
Estimating the term…
Abstract
FSH mutants with increased glycosylation and longer half-lives are described. The use of FSH mutants for inducing folliculogenesis in human patients is also described.
Claims10
An isolated mutant follicle stimulating hormone (FSH) comprising a β-subunit and an α-subunit, wherein the β-subunit comprises SEQ ID NO:
- 3 and the α-subunit comprises SEQ ID NO:
- 4 or 5.
A composition comprising a pharmaceutically acceptable carrier or excipient and a mutant (FSH) comprising a β-subunit and an α-subunit, wherein the β-subunit comprises SEQ ID NO:
- 3 and the α-subunit comprises SEQ ID NO:
- 4 or 5.
Dependencies are inferred from the claim text.