Imaging, diagnosis and treatment of disease
AssigneeCancer Research Technology Limited
InventorsRoy Bicknell, Lukasz Huminiecki
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Abstract
The present invention relates to endothelial cell-specific genes and encoded polypeptides and materials and uses thereof in the imaging, diagnosis and treatment of conditions involving the vascular endothelium.
Claims17
A method of imaging vascular endothelium in the body of an individual, the method comprising administering to the individual an effective amount of a compound comprising a moiety which selectively binds to a polypeptide having at least 90% identity to the amino acid sequence of SEQ ID NO:37 or SEQ ID NO:24, and a further moiety.
A method of diagnosing or prognosing in an individual a condition which involves the vascular endothelium, the method comprising administering to the individual an effective amount of a compound comprising a moiety which selectively binds to a polypeptide having at least 90% identity to the amino acid sequence of SEQ ID NO:37 or SEQ ID NO:24, and a further moiety.
Dependencies are inferred from the claim text.