Expandable fluoropolymer device for delivery of therapeutic agents and method of making

A method of manufacturing a radially expandable fluid delivery device, comprising:

• providing a tube of biocompatible fluoropolymer material having a microstructure of nodes interconnected by fibrils, wherein the microstructure has a predetermined porosity based on an extrusion and expansion forming process;
• applying a radial expansion force to the tube to plastically deform the tube by expanding the tube beyond the tube's elastic limit to a predetermined diameter dimension;
• and
• removing the radial expansion force;
• wherein the tube is radially inelastic while sufficiently pliable to be collapsible and inflatable from a collapsed configuration to an expanded configuration upon introduction of an inflation force, such that the expanded configuration occurs upon inflation to the predetermined diameter dimension;
• and
• wherein the microstructure includes at least one microporous portion of micro-channels and the predetermined porosity is sufficient for a fluid to inflate the fluid delivery device and permeate through the at least one microporous portion of micro-channels at a controlled rate of permeation.