Process for producing a stent for angioplasty
AssigneeSorin Biomedica Cardio S.p.A.
InventorsMaria Curcio, Giovanni Rolando, Franco Vallana
Life of this patent
Estimating the term…
Abstract
A stent has surface sculpturing, preferably on its outer surface only, having, for example, microspheres, having the function of increasing the actual geometric surface area of the stent, of creating undercuts and roughness to encourage the application of coatings of active or activatable agents, as well as of improving the attachment of the stent to the blood vessel wall.
Claims57
An improved process for producing a stent for angioplasty, said improvement comprising:
- prior to cutting a microtube, creating on said microtube a plurality of regions thereon for an active agent to be optionally placed;
- and
- polishing said stent.
A process comprising, applying to a microtube blank the following sequence of steps:
- first, creating a plurality of surface areas on said blank that optionally contact an active agent, and second, cutting a stent structure into said microtube blank.
A process of forming a drug carrying stent from a microtube, the microtube having an exterior surface and an interior surface defining a wall thickness therebetween, the stent having a generally cylindrical structure with a plurality of apertures and a plurality of locations for containing a drug, the apertures having a shape which increases in size when the stent is expanded, the locations for containing a drug having a shape which is substantially unchanged when the stent is expanded, the process comprising:
- controlling a laser cutting machine to cut both the apertures and the locations for containing a drug into the microtube during a stent forming process, the locations for containing a drug being cut to a depth which is less than the wall thickness.
An improved process for producing a stent for angioplasty, said improvement comprising, prior to cutting stent structure apertures into a microtube, creating on said microtube a plurality of regions thereon for an active agent to be optionally placed.
A process comprising, applying to a microtube blank the following sequence of steps:
- first, creating a plurality of surface areas on said blank, second, cutting said microtube blank, and after said first step, contacting said plurality of surface areas with said active agent.
A process of forming a drug carrying stent from a microtube, the stent having a generally cylindrical structure with a plurality of apertures and a plurality of locations for containing a drug, the apertures having a shape which increases in size when the stent is expanded, the locations for containing a drug having a shape which is substantially unchanged when the stent is expanded, the process comprising:
- controlling a laser cutting machine to cut both the apertures and the locations for containing a drug into the microtube during a stent forming process, wherein the locations for containing a drug are cut before the apertures are cut.
A process comprising, applying to a microtube blank the following sequence of steps:
- first, creating a plurality of surface areas on said blank, second, cutting said microtube blank and, after said first step, contacting said plurality of surface areas with more than one active agent.
A process comprising, applying to a microtube blank the following sequence of steps:
- first, creating a plurality of surface areas on said blank that contact an active agent, the active agent being selected from the group consisting of an antithrombogenic agent, an agent for resisting restenosis, and an agent to resist tissue proliferation, and second, cutting said microtube blank.
A process comprising, applying to a microtube blank the following sequence of steps:
- first, creating a plurality of surface areas on said blank that optionally contact an active agent;
- second, cutting said microtube blank;
- and
- wherein the process further comprises polishing a surface of the microtube blank.
A process comprising, applying to a metal microtube blank the following sequence of steps:
- first, creating a plurality of surface areas on said blank that optionally contact an active agent, and second, cutting said microtube blank.
Dependencies are inferred from the claim text.