US 7,736,658 B2 · Canine combination vaccines

Abstract

This invention relates to vaccines and methods for protecting dogs against disease caused by Bordetella bronchiseptica. This invention also relates to combination vaccines and methods for protecting dogs against disease or disorder caused by canine pathogens, for example, infectious tracheobronchitis caused by Bordetella bronchiseptica, canine distemper caused by canine distemper (CD) virus, infectious canine hepatitis (ICH) caused by canine adenovirus type 1 (CAV-1), respiratory disease caused by canine adenovirus type 2 (CAV-2), canine parainfluenza caused by canine parainfluenza (CPI) virus, enteritis caused by canine coronavirus (CCV) and canine parvovirus (CPV), and leptospirosis caused by Leptospira Bratislava, Leptospira canicola, Leptospira grippotyphosa, Leptospira icterohaemorrhagiae or Leptospira pomona. The vaccines of the present invention include a Bordetella bronchiseptica p68 antigen.

Claims11

Dependent claims

A combination vaccine for immunizing a dog against canine pathogens comprising a preparation of a therapeutically effective amount of an attenuated strain of canine distemper (CD) virus, an attenuated strain of canine adenovirus type 2 (CAV-2), an attenuated strain of canine parainfluenza (CPI) virus and an attenuated strain of canine parvovirus (CPV);

an inactivated whole or partial cell preparation of a strain of canine coronavirus (CCV), a Bordetella bronchiseptica p68 protein, and an adjuvant, wherein said Bordetella bronchiseptica p68 antigen comprises the amino acid sequence as set forth in SEQ ID NO:
1 and is produced recombinantly.

Dependencies are inferred from the claim text.

Canine combination vaccines

Life of this patent

Canine combination vaccines

Life of this patent

Abstract

Claims11