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US 7,734,427 B2Granted
System, method and computer program for non-binary sequence comparison
AssigneeBioInformatica LLC
InventorJeffrey M. Clark
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Abstract
A system and method for performing non-binary comparison of biological sequences includes a new measure ω0, which is a non-binary counting measure that is used in a stand alone module called VaSSA-1. This measure obtains substantially more information about sequences and comparisons between them than is gathered by conventional bioinformatics techniques.
Claims4
A computer-implemented method for analyzing and determining structural behavior patterns of nucleotide sequences, comprising:
- reading a sequence file;
- selecting a target sequence and a base sequence from said file;
- performing a non-binary comparison between each base pair of said target and said base
- sequences using a computer system to generate an ω0 similarity score;
- and
- determining a similarity between said target and said base sequences based on said similarity scores.
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