Process for obtaining pure oseltamivir
AssigneeHetero Drugs Limited
InventorsBandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Rapolu Raji Reddy, Dasari Muralidhara Reddy, Kesireddy Subash Chander Reddy
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Abstract
The present invention provides a process for obtaining highly pure crystalline form of oseltamivir free base, thus, for example, suspending or dissolving impure or non-crystalline oseltamivir free base in a hydrocarbon solvent and then isolating crystals to obtain oseltamivir free base in well defined crystalline form. The present invention also provides a process for preparation of oseltamivir phosphate in high purity.
Claims11
A process for preparation of pure oseltamivir phosphate, which comprises contacting a solution or suspension of an organic acid addition salt of oseltamivir with a solution of phosphoric acid in an alcoholic solvent and then isolating pure oseltamivir phosphate from the solution.
Dependencies are inferred from the claim text.