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AssigneeAgensys, Inc.
InventorsArthur B. Raitano, Pia M. Challita-Eid, Mary Faris, Rene S. Hubert, Wangmao Ge, Aya Jakobovits
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A novel gene 0193P1E1B (also designated 193P1E1B) and its encoded protein, and variants thereof, are described wherein 193P1E1B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 193P1E1B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 193P1E1B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 193P1E1B can be used in active or passive immunization.
An isolated polynucleotide which comprises the nucleic acid sequence of SEQ ID NO:8 from residue 805 to 2043, SEQ ID NO:10 from residue 805 to 2043 or SEQ ID NO:12 from residue 805 to 2043.
Dependencies are inferred from the claim text.