Isolated antibody specific for a mammalian MDM2 binding protein comprising SEQ ID No. 2 or 4
AssigneePhiladelphia Health and Education Corporation
InventorsMark Thomas Boyd, Dale Stewart Haines, Nikolina Vlatkovic
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Abstract
Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. In addition, methods and compositions for modulating the G1 phase of the cell cycle via altering expression and/or activity of a mammalian MDM2 binding protein are provided.
Claims1
An isolated antibody specific for a mammalian MDM2 binding polypeptide (MTBP) comprising SEQ ID NO:
- 2 or 4, wherein said antibody is raised against a mammalian MTBP polypeptide comprising SEQ ID NO:
- 2 or 4.
Dependencies are inferred from the claim text.