Coating for controlled release of drugs from implantable medical devices

A coating for an implantable medical device comprising a polymer having the chemical formula:

• [—CH2CH2—/—CH2CH(R)—/—CH2CH(OH)—]p(m,n,o)
• wherein:
• R is selected from a group consisting of alkyl-O—, alkylsulfonyl-O—, NHR1, phenyl, alkylphenyl, trifluoromethyl, perfluoroalkyl, R1HNC(O)—, R1HNC(O)O— and a macromolecule, wherein:
• the alkyl group of the alkyl-O—, or alkylsulfonyl-O— is unsubstituted, partially fluorinated or fully fluorinated;
• R1 is selected from the group consisting of monomethylated poly(ethylene glycol), poly(propylene glycol), poly(vinylpyrrolidone), poly(acrylamide), poly(2-hydroxyethylmethacrylate), a phospholipid, heparin, low molecular weight heparin, a heparinoid, hyaluronic acid and albumin;
• the macromolecule is selected from the group consisting of poly(ethylene glycol), poly(propylene glycol), poly(vinylpyrrolidone), poly(acrylamide), poly(2-hydroxyethylmethacrylate), a phospholipid, heparin, low molecular weight heparin, a heparinoid, hyaluronic acid, albumin and a polysiloxane;
• m is the mol percent CH2CH2— in the polymer and is from about 20 to about 80;
• n is the mol percent CH2CH(R)— in the polymer and is from about 1 to about 40;
• o is the mol percent CH2CH(OH)— in the polymer and is (100−(m+n));
• and,
• p is from about 20,000 Da to about 500,000 Da.