Nateglinide-containing preparation
AssigneeAjinomoto Co., Inc.
InventorsChisato Makino, Erika Motomura, Kunikazu Suzuki, Takahiko Andou, Nobutaka Ninomiya, Akira Yabuki
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Abstract
The present invention provides a small-sized preparation that is easy to take, containing 26% or more of nateglinide and 28% or more of at least one disintegrant selected from the group consisting of carmellose or salts thereof, sodium carboxymethyl starch, croscarmellose sodium, crospovidone, partly pregelatinized starch and low-substituted hydroxypropyl cellulose, based on the total mass of the preparation. The preparation of the present invention has high contents of nateglinide, which can be absorbed immediately to exhibit a hypoglycemic action.
Claims15
A tablet comprising nateglinide, wherein the nateglinide is contained in an amount of 50 mass % or more based on the total mass of the tablet, and at least one disintegrant selected from the group consisting of carmellose or salts thereof, sodium carboxymethyl starch, croscarmellose sodium, crospovidone, partly pregelatinized starch and low-substituted hydroxypropyl cellulose is contained, wherein the total amount of the disintegrant is 35 mass % or more based on the total mass of the tablet.
Dependencies are inferred from the claim text.